For the outside world, exactly who wins Nobel Prizes in the science is fairly academic (geddit?) - and even for those with a professional interest it may sometimes seem that the reason for the awards can be sliced pretty thin these days. The early prizes do seem often to have been for more 'big' work than the more subtle modern ones. But having said that, we also always get some goodies. I didn't realize it until they sent me a press release, but Thomson Reuters do an annual prediction of the likely runners and riders - useful in case you fancy a flutter. So here are this years' favourites according to TR. On the physics side, I rather fancy the Quantum Spin Hall effect, but that's just me... P.S. I don't know why Economics is treated as a science either. PHYSIOLOGY or MEDICINE James E. Darnell, Jr. Vincent Astor Professor Emeritus, Laboratory of Molecular Cell Biology, Rockefeller University New York, NY USA -and- Robert G. Roeder Arnold...